Respiratory allergy
The ARISE Trial
Allergic rhinitis (also known as hay fever) affects one in four Australians, but many do not use their treatment nasal spray properly – leading to ongoing symptoms.
The Allergic Rhinitis Improvement through Strategic Education (ARISE) Trial aims to find out if a specifically designed education package used alongside a daily nasal spray can help reduce symptoms and improve quality of life for young people with the condition.
Overview
Hay fever is the most common allergy in the country. However, most people do not seek medical care – and those that do use nasal sprays often don’t use them as consistently or for as long as recommended.
Poor control of symptoms can lead to decreased physical and mental health and underperformance at school and work.
To help improve how young people manage hay fever, the National Allergy Centre of Excellence (NACE) launched The ARISE Trial in March 2025. Participants were randomised into one of two groups.
Recruitment has now closed.
Group 1: Enhanced Education Package
Participants in this group receive repeat weekly notifications for six weeks. These SMS and email alerts include links to education resources, correct technique for using their nasal spray, dosing frequency, pollen count updates, relevant information sheets and articles.
Group 2: Standard Education
Participants in this group will not receive any additional education beyond their usual standard of care, which may include management by a general practitioner, specialist, pharmacist, or self-management.
Researchers will assess whether the specifically designed education package reduces symptoms and improves quality of life, compared to standard care delivered by your doctor.
Up to $150 of vouchers available for taking part!
Who could take part:
14 to 29 year olds who have been:
- Diagnosed with hay fever
- Recommended a daily nasal spray containing steroids for hay fever treatment
What’s involved over nine months:
- Attend three short video calls with the study team – which takes 15-30 minutes
- Complete three short online questionnaires – which takes 15 minutes
- Follow the educational resources provided
- Receive a $50 voucher after each video call
Recruitment clinics
- Victoria: The Alfred, Melbourne Allergy Asthma & Immunology Consultants, Goulburn Valley Health, Melbourne Allergy Centre & Children’s Specialists (MACCS), The Royal Children’s Hospital, Latrobe Regional Health, Surrey Hills Medical Centre, Wangaratta Medical Centre
- South Australia: Adelaide Allergy and Immunology Centre
- Western Australia: Perth Allergy
- Northern Territory: Royal Darwin Hospital, Darwin Children’s Clinic, Territory Medical Group
- Queensland: Compass Immunology Clinic (Main Clinic, Mount Gravatt, Compass Kids, Toowoomba), Allergy Medical Centre Townsville, Specialist Network Benowa
- NSW: Campbelltown Hospital, Trinity Medical Centre Wagga, The Children's Clinic
- ACT: Canberra Allergy
- Tasmania: Allergy Tasmania
*A referral from your GP may be required to attend a specialist site. **Private consultation fees may be charged at some sites.
Study team
- Professor Connie Katelaris, Chief Investigator
- Associate Professor Joy Lee, Chief Investigator
- NACE Respiratory Allergy Stream Advisory Group
- Evie Kayes, NACE Research Manager
Learn more about the ARISE Trial and read the Frequently Asked Questions!
Interested in other respiratory allergy studies?
Visit the NACE Allergy Studies Directory for a list of clinical trials, cohort and registry studies recruiting across Australia.
Want to help shape how allergy research is done?
Share your experiences of having allergic rhinitis with researchers, check out the NACE Consumer Engagement Register.
In proud partnership with
